Another example of the importance of the basic solubility properties of organic functional groups is in the solubility of the simple sugars. Ask yourself, if triglycerides are so much more energy dense than carbohydrates, why are sugars the basic nutrient molecule for metabolism. The answer is solubility. Because of its numerous hydroxyl groups, glucose (and other simple sugars) can readily hydrogen bond with water. Simple sugars are water soluble in any proportion.