Subsequent to oxidation of glyceraldehyde 3-phosphate by NAD+ to form 1,3 biphosphoglycerate (BPG), is the formation of two molecules of 3-phosphoglycerate and two molecules of ATP. What's going on? Aside from the NADH produced earlier, which is not of bioenergetic purpose in the anaerobic context, the steps of glycolysis have been devoted to producing BPG. The formation of 3-phosphoglycerate and ATP from 1,3 biphosphoglycerate (1-3-BPG) and ADP is spontaneous because the phosphate bonds of 1,3-biphosphoglycerate hold even more free energy than those of ATP.
![]() ![]() WikiPremed is a trademark of Wisebridge Learning Systems LLC. The work of WikiPremed is published under a Creative Commons Attribution NonCommercial ShareAlike License. There are elements of work here, such as a subset of the images in the archive from WikiPedia, that originated as GNU General Public License works, so take care to follow the unique stipulations of that license in printed reproductions. |